There are many quality educational institutions in the Greater Poplar Bluff area.
| Institution | Type | Number | Students |
| Elementary Schools | Public |
7 |
2755 |
| Fifth & Sixth Grade Center | Public |
1 |
735 |
| Poplar Bluff Junior High | Public |
1 |
715 |
| Poplar Bluff Senior High | Public |
1 |
1261 |
| Technical Career Center | Public |
1 |
299 |
| Three Rivers Community College | Public |
1 |
4400 |
| William Woods University | Public |
1 |
|
| Sacred Heart Catholic School | Private |
1 |
180 |
| Westwood Baptist Academy | Private |
1 |
165 |